Medical Dictionary

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P Receptor, Substance

A class of cell surface receptors for tachykinins with a preference for substance P. Neurokinin-1 (NK-1) receptors have been cloned and are members of the G protein coupled receptor superfamily. They are found on many cell types including central and peripheral neurons, smooth muscle cells, acinar cells, endothelial cells, fibroblasts, and immune cells.

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