Medical Dictionary

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4-Nitrophenol-2-Hydroxylase

A polymorphic enzyme that activates carcinogenic N-nitrosamines, benzene, urethane, and other low molecular weight compounds. It is inducible by ethanol and metabilizes alcohol. Experimentally, it is used to study the effects of ethanol usage and withdrawal via enzyme markers such as N-nitrosodimethylamine demethylase. (Pharmacogenetics 1995;5 Spec No:S141-4) EC 1.5.99.-.

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